Screening de novo designed protein binders in unpurified lysate
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Functional and structural data in a single measurement
Problem
Computational design produces binders at scale, but screening themefficiently is the bottleneck. Traditional validation does not provide structural data, requirespurified material and multiple assays to determine whether a design binds with sufficientaffinity and stability, slowing down the transition from design to decision.
Solutions
By providing functional and structural data in a single measurement and directly from crude expression material, FIDA allows evaluation of binding, stability, and solution behaviour at an early stage. This shifts validation from a sequential, resource-intensive process to an early, decision-driven step.
How to screen de novo design protein binders in unpurified lysate using flow induced dispersion analysis?
Lear about streamline binder
Screening de novo designed protein bindersin unpurified lysate using flow induceddispersion analysis
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