Let us send you the file to your email.
If you wish, you can choose to receive more literature on the topic by agreeing to receive other communication.
You will receive the file on your email.
The Protein Binder Printer: Fully Automated Closed-Loop AI-Driven Protein Binder Design
Diego Ruiz Espi; G. Avelar Molina; A. Ljungars A. Hald;, E. Rivera de Torre; T.P. Jenkins
This poster from the Technical University of Denmark and Novo Nordisk demonstrates a fully automated, closed-loop AI-driven pipeline for designing protein binders, with Flow Induced Dispersion Analysis (FIDA) used to validate the binding of the computationally designed candidates in solution. FIDA confirmed high-affinity binders — for example an anti-ubiquitin binder with picomolar target affinity — closing the design-build-test loop. It is an example of using FIDA to validate binding affinity of de novo, AI-designed protein binders.
