Dig deeper:
Applications, Webinars, Posters
Publications and more...
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Publications
In-Solution Characterization of Extracellular Vesicles: A New Approach to Evaluating Antibody Binding and Surface Interactions
Author Information
Maria-Anthi Kakavoulia, Peter Spies, Tanja J. Kutzner, Tobias Tertel, Sophie Franzmeier, Samir El Andaloussi, Bernd Giebel, Herbert Kaltner, Dominik Meinel, André Görgens, Anna-Kristin Ludwig
Journal of Extracellular Vesicles 2026
Publications
2026
Posters
Engineering Galectin-1 Valency to Promote Glycan-Dependent MSC-EV Association
Author Information
Maria Anthi Kakavoulia, Tobias Tertel, Peter Spies, Dominik Meinel, Bernd Lepenies, Bernd Giebel, Tanja-Jasmin Kutzner, Anna-Kristin Ludwig
Posters
2026
Publications
De novo designed single-domain antibodies protect against lethal cobra venom neurotoxicity in vivo
Author Information
Max D. Overath, Emil V. S. Lundquist, Kasper H. Björnsson, Samuel Kerwin, Christian P. Jacobsen, Mark von Bülow Møiniche, Diego Ruiz Espi, Kim Boddum, Melisa Benard-Valle, Monica L. Fernández-Quintero, Stephen P. Mackessy, Timothy P. Jenkins
bioRxiv (preprint) 2026
Publications
2026
Posters
The importance of monomer conformation in amyloid formation of α-synuclein splice variants
Author Information
Katherine M. Dewison, Alexander I. P. Taylor, David J. Brockwell, Sheena E. Radford
Posters
2025
Videos
De Novo Protein Screening: Snake Venom to Cancer, Designing Binders Faster Than We Can Measure Them
Author Information
Timothy Jenkins, Ph.D.
Videos
2026
Publications
The rise of state-centric biophysics: integrating orthogonal molecular readouts across biophysical scales
Author Information
The rise of state-centric biophysics: integrating orthogonal molecular readouts across biophysical scales
Paulo Roberto Dores-Silva, Todd Willian Pascarella, Jason Michael Newman, Júlio César Borges
Biophysical Reviews
Publications
2026
Videos
The new Fida Instrument: Fida Evolve: how does it differ and what do the users think?
Author Information
Jan Nowak, Ph.D.; Hasse Hedeby
Videos
2026
Publications
Paraspeckle condensation is controlled via TDP-43 polymerization and linked to neuroprotection
Author Information
Hodgson, R.E., Huang, WP., Lang, R. et al.
Nature Cell Biology 2026
Publications
2026
Publications
HMA proteins produce 2',3'-cNMP signaling molecules and activate CNL-mediated immunity in rice
Author Information
Xiangyu Gong, Guoqing Niu, Shuyi Sun, Bingxiao Yan, Ziqiang Li, Wei Tang, Pei Hu, Huakun Zheng, Meilian Chen, Nicolas Ponceler, Zhougeng Xu, Xing Lv, Hui Lin, Jiyun Liu, Yuanyuan Gao, Lu Zhu, Xin Wang, Guo-Liang Wang, Didier Tharreau, Houxiang Kang, Yiwen Deng, Zonghua Wang, Yu Zhang, Zuhua He
bioRxiv (preprint) 2026
Publications
2026
Publications
Bright Single-Cell Fluorescent Reporter Enables Ultrasensitive Target Detection for Microbial Cell-Based Biosensors
Author Information
Faying Zhang, Xuting Sun, Hui Zheng, Meng Mei, Li Yi, Guimin Zhang
ACS Sensors 2026
Publications
2026
Application Notes
Reversible oligomerization and FIDA: From label free detection to oligomerization Kd determination.
Author Information
Reversible oligomerization and FIDA: From label free detection to oligomerization Kd determination.
Emil G. P. Stender, PhD; Kritika Sahni Ray, Dr.rer.nat.; Henrik Jensen, Ph.D.
Application Notes
2026
Application Notes
FIDA in a clinical setting: Determination of shifting sphingosine 1-phosphate (S1P) binding to its carrier molecules serum albumin (SA) and high-density lipoprotein (HDL)
Author Information
FIDA in a clinical setting: Determination of shifting sphingosine 1-phosphate (S1P) binding to its carrier molecules serum albumin (SA) and high-density lipoprotein (HDL)
Prof. Dr. Markus H. Gräler, Jena University Hospital, Jena, Germany
Application Notes
2026
Literature
Rapid, Precise Information for Fast and Safe Drug Development
Based on our revolutionary, patented FIDA technology, Fidabio offers rapid, precise information on complex binding interactions and concentration of proteins, particles up to 1,000 nm Dh, antibodies, and other biomolecules.
The core measurements of the FIDA technology, or Flow-Induced-Dispersion- Analysis, are very precise and reproducible, absolute detections of hydrodynamic radii directly in plasma, serum, fermentation media, cell lysate etc. with accuracies of +/- 5 %, coefficient of variations of <5 % and a sensitivity of 0.1 nM FITC type tags. The instrument is fully automated for vials or 2 x 96 wells plates with end-to-end temperature control from 4-55 °C controllable in increments of 0.1 °C. Each test only requires a few hundred nanoliters of sample material.
The FIDA technology provides significant advantages over current technologies in terms of data quality, cost, versatility and time. In other words, Fidabio enables scientists and researchers to carry out tests that are impossible using current technologies leading to faster and safer drug development.
The core measurements of the FIDA technology, or Flow-Induced-Dispersion- Analysis, are very precise and reproducible, absolute detections of hydrodynamic radii directly in plasma, serum, fermentation media, cell lysate etc. with accuracies of +/- 5 %, coefficient of variations of <5 % and a sensitivity of 0.1 nM FITC type tags. The instrument is fully automated for vials or 2 x 96 wells plates with end-to-end temperature control from 4-55 °C controllable in increments of 0.1 °C. Each test only requires a few hundred nanoliters of sample material.
The FIDA technology provides significant advantages over current technologies in terms of data quality, cost, versatility and time. In other words, Fidabio enables scientists and researchers to carry out tests that are impossible using current technologies leading to faster and safer drug development.
Fida 1 Overview
Fida 1 Fundamentals: Assessment of Sample Quality with every measurement
Poster: Assessment of sample quality with every measurement – Fida 1 Fundamentals
Technote: The Relationship between hydrodynamic radius and molecular weight
Analysis of Large Particles
The FIDA technology allows the analysis of proteins and particles 0.5 to 1,000 nm in diameter. This enables analysis of exosomes, liposomes, vaccines, viral vectors, membrane-embedded proteins, intrinsically disordered proteins et. al.
With the Fidabio instrument you can amongst others analyse interactions between targets and membrane proteins and vaccines, characterization of exosomes, liposome and IDPs, quantification of specific exosomes in plasma, quantification of viral vectors in fermentation media etc.
With the Fidabio instrument you can amongst others analyse interactions between targets and membrane proteins and vaccines, characterization of exosomes, liposome and IDPs, quantification of specific exosomes in plasma, quantification of viral vectors in fermentation media etc.
Analysis Directly in Complex Matrices
It is well-known that detection in a buffer, sample preparations and immobilization from time to time impact the data reliability. Detection directly under native conditions ensures you that your decisions are based on the most biologically accurate data.
The FIDA technology is based on in-solution measurements. You can analyze directly in plasma, serum, cell lysate, fermentation media, CHO cells et al. Background noise is eliminated by an automatic adjustment of the baseline and the risk of adsorption is managed with our advanced, proprietary capillary coating.
The FIDA technology is based on in-solution measurements. You can analyze directly in plasma, serum, cell lysate, fermentation media, CHO cells et al. Background noise is eliminated by an automatic adjustment of the baseline and the risk of adsorption is managed with our advanced, proprietary capillary coating.
In-solution Validation Immobilization Data
SPR and BLI are industry standards and are widely used for amongst others affinity Kd determination. Though often robust and reliable, occasionally the surface immobilization might result in difficult-to-interpret artefacts due to mass transport limitations.
With easy setup and validation of new assays and the consumption of only a few hundred nanoliters of sample material, the Fidabio instrument offers a possibility of fast and accurate orthogonal validation of Kd data generated with SPR, BLI etc.
With easy setup and validation of new assays and the consumption of only a few hundred nanoliters of sample material, the Fidabio instrument offers a possibility of fast and accurate orthogonal validation of Kd data generated with SPR, BLI etc.
