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Protein analysis and characterisation
Protein stability and storage

What types of aggregates are there and how do they show in FIDA data?

Different types of aggregates can be observed with FIDA: soluble diffusive aggregates and insoluble non-diffusive aggregates.
Soluble aggregates will register as a shoulder or bump on the Taylor-gram.

While insoluble aggregates will register as a signal spike.

The soluble kind can be quantified by their total fluorescent area by fitting multiple species.

The insoluble ones can be counted by counting the spikes, as each spike is at least one aggregate, as explained here.